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Mara Sherman |
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Jin Zhang |
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Nicole Walsh |
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Jin Zhang |
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| 05/21/2009 |
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Nicole Walsh |
CtIP-BRCA1 modulatse the choice of DNA double-strand-break repair pathway throughout the cell cycle. Yun MH, Hiom K. Nature. 2009 Apr 8, e pub. [link] |
| 01/15/2009 |
Jin Zhang |
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Ivan K. |
Regulation of mitochondrial structure and function by the F1F0-ATPase inhibitor protein. Campanella M, et. al. Cell Metab. 2008 Jul;8(1):13-25[link] |
| 8/28/2008 |
Matt Frank |
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation. Guo W, et. al. Nature, 2008 May 22;453(7194):529-33. Epub 2008 May 7.[link] |
| 8/28/2008 |
Mara Sherman |
MIRF4 addiction in multiple myeloma. Shaffer L , et. al. Nature, 2008 Jul 10;454(7201):172-3.[link] |
| 7/31/2008 |
Mike T. |
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties. Cancer Cell. 2008 Jul 8; 14(1): 47-58 [link] |
| 8/17/2007 |
Wei Bo |
DNA repair is limiting for haematopoietic stem cells during ageing. Nature. 2007 Jun 7; 447(7145): 686-90 [link] |
| Break |
|
Journal Club Reconstituted |
| 6/22/2006 |
Kathy S. |
Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell. 2006 Jun 2;125(5):929-41 [link] |
| 6/08/2006 |
Mike T. |
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006 May 25;441(7092):475-82 [link] |
| 5/25/06 |
Hsiao-Wen |
c-Myc phosphorylation is required for cellular response to oxidative stress. Mol Cell. 2006 Feb 17;21(4):509-19 [link] |
| 5/04/06 |
Cynthia |
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005 Oct 28;310(5748):644-8 [link] |
| 4/13/06 |
Matt |
The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression. Oncogene. 2006 Jan 12;25(2):186-97. [link] |
| 3/30/06 |
Sam E. |
The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells. Cancer Cell. 2006 Mar;9(3):175-187[link] |
| 3/16/2006 |
Jerry |
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18081-6. Epub 2005 Dec 5 [link] |
| 3/02/2006 |
Deepa |
Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell. 2006 Jan 27;124(2):407-21 [link] |
| 2/2/2006 |
Kentaro |
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell. 2005 Oct 21;123(2):207-18 [link] |
| 1/19/2006 |
Kelly |
Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature 2005 Dec 15;438(7070):981-7 [link] |
| 1/5/2006 |
Gary |
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005 Nov;8(5):369-80 [link] |
| 12/8/2005 |
Dave |
Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell 8:275-285, 2005 [link] |
| 11/10/2005 |
Daphne |
Cytoskeletal remodelling and slow dynamics in the living cell. Nature Materials 4:557-561, 2005 [link] |
| 10/27/2005 |
Sam F |
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genetics 37:1047-1054, 2005 [link] |
| 9/29/2005 |
Hsiao-Wen |
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7:77-85, 2005 [link] |
| 9/15/2005 |
Mike |
PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53. Science 309:1732-1735, 2005 [link] |
| 9/1/2005 |
Matt |
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature 436:807-811, 2005 [link] |
| 8/18/2005 |
Cynthia |
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436:725-730, 2005 [link] |
| 8/4/2005 |
Ali |
Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121:823-835, 2005 [link] |
| 7/21/2005 |
Rhine |
A genetic screen for candidate tumor suppressors identifies REST. Cell 121:837-848, 2005 [link] |
| 7/7/2005 |
Sarah |
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nature Cell Biology 7:195-201, 2005 [link] |
| 6/23/2005 |
Dave |
Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nature Medicine 11:71-76, 2005 [link] |
| 6/2/2005 |
Daphne |
Observation of nuclear fusion driven by a pyroelectric crystal. Nature 434:1115-1117, 2005 [link] |
| 5/19/2005 |
Mike |
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 121:179-193, 2005 [link] |
| 5/5/2005 |
Matt |
hDOT1L links histone methylation to leukemogenesis. Cell 121:167-178, 2005 [link] |
| 4/21/2005 |
Sam |
Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120:675-685, 2005 [link] |
| 4/14/2005 |
Hsiao-Wen |
Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Research 65:1655-1663, 2005 [link] |
| 3/3/2005 |
Cynthia |
Oncogene, adv online pub [link] |
| 2/17/2005 |
Ali |
Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nature Med 10:1329-1355, 2004 [link] |
| 2/3/2005 |
Rhine |
Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 433:278-285, 2005 [link] |
| 1/20/2005 |
Sarah |
Genome-wide survey of protein kinases required for cell cycle progression. Nature 432:980-987, 2004 [link] |
| 1/6/2005 |
Dave |
Gastric cancer originating from bone marrow-derived cells. Science 306: 1568-1571, 2004 [link] |
| 12/9/2004 |
Mike |
The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature 432:635-639, 2004 [link] |
| 11/11/2004 |
Daphne |
Efficient active transport of gene nanocarriers to the cell nucleus. PNAS 100:3878-3882, 2004 [link] |
| 10/28/2004 |
Mike |
MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell 119:75-86, 2004 [link] |
| 10/14/2004 |
Mike |
Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. J Biol Chem 2004 Dec 17;279(51):53407-18 [link] |
| 9/23/2004 |
Matt |
Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 2004 Oct 8;306(5694):279-83 [link] |
| 9/2/2004 |
Ksenia |
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004 428:332-337 [link] |
| 8/19/2004 |
Sam |
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117:773-786, 2004 [link] |
| 8/5/2004 |
Hsaio-Wen |
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol. 2004 May;6(5):386-8 [link] |
| 7/22/2004 |
Rhine |
Separate domains of AID are required for somatic hypermutation and class-switch recombination.
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| 7/8/2004 |
Francesca |
Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer Research 64:3871-3877, 2004 [link] |
