Teitell Lab > Journal Club

Journal Club presentations are held from 12-1pm in Life Sciences (LS) 2320.

Papers Presented from July 1, 2004 Onward:

Date	Presenter	Citation
8/17/2007	Wei Bo	DNA repair is limiting for haematopoietic stem cells during ageing. Nature. 2007 Jun 7; 447(7145): 686-90 [link]
Break		Journal Club Reconstituted
6/22/2006	Kathy S.	Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway. Cell. 2006 Jun 2;125(5):929-41 [link]
6/08/2006	Mike T.	Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature. 2006 May 25;441(7092):475-82 [link]
5/25/06	Hsiao-Wen	c-Myc phosphorylation is required for cellular response to oxidative stress. Mol Cell. 2006 Feb 17;21(4):509-19 [link]
5/04/06	Cynthia	Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005 Oct 28;310(5748):644-8 [link]
4/13/06	Matt	The tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expression. Oncogene. 2006 Jan 12;25(2):186-97. [link]
3/30/06	Sam E.	The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells. Cancer Cell. 2006 Mar;9(3):175-187[link]
3/16/2006	Jerry	MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18081-6. Epub 2005 Dec 5 [link]
3/02/2006	Deepa	Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow. Cell. 2006 Jan 27;124(2):407-21 [link]
2/2/2006	Kentaro	The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis. Cell. 2005 Oct 21;123(2):207-18 [link]
1/19/2006	Kelly	Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature 2005 Dec 15;438(7070):981-7 [link]
1/5/2006	Gary	TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005 Nov;8(5):369-80 [link]
12/8/2005	Dave	Global loss of imprinting leads to widespread tumorigenesis in adult mice. Cancer Cell 8:275-285, 2005 [link]
11/10/2005	Daphne	Cytoskeletal remodelling and slow dynamics in the living cell. Nature Materials 4:557-561, 2005 [link]
10/27/2005	Sam F	The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genetics 37:1047-1054, 2005 [link]
9/29/2005	Hsiao-Wen	Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. Cancer Cell 7:77-85, 2005 [link]
9/15/2005	Mike	PUMA Couples the Nuclear and Cytoplasmic Proapoptotic Function of p53. Science 309:1732-1735, 2005 [link]
9/1/2005	Matt	Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature 436:807-811, 2005 [link]
8/18/2005	Cynthia	Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436:725-730, 2005 [link]
8/4/2005	Ali	Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121:823-835, 2005 [link]
7/21/2005	Rhine	A genetic screen for candidate tumor suppressors identifies REST. Cell 121:837-848, 2005 [link]
7/7/2005	Sarah	The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nature Cell Biology 7:195-201, 2005 [link]
6/23/2005	Dave	Inhibitors of histone deacetylases induce tumor-selective apoptosis through activation of the death receptor pathway. Nature Medicine 11:71-76, 2005 [link]
6/2/2005	Daphne	Observation of nuclear fusion driven by a pyroelectric crystal. Nature 434:1115-1117, 2005 [link]
5/19/2005	Mike	Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 121:179-193, 2005 [link]
5/5/2005	Matt	hDOT1L links histone methylation to leukemogenesis. Cell 121:167-178, 2005 [link]
4/21/2005	Sam	Control of cell proliferation and apoptosis by mob as tumor suppressor, mats. Cell 120:675-685, 2005 [link]
4/14/2005	Hsiao-Wen	Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Research 65:1655-1663, 2005 [link]
3/3/2005	Cynthia	Oncogene, adv online pub [link]
2/17/2005	Ali	Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nature Med 10:1329-1355, 2004 [link]
2/3/2005	Rhine	Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature 433:278-285, 2005 [link]
1/20/2005	Sarah	Genome-wide survey of protein kinases required for cell cycle progression. Nature 432:980-987, 2004 [link]
1/6/2005	Dave	Gastric cancer originating from bone marrow-derived cells. Science 306: 1568-1571, 2004 [link]
12/9/2004	Mike	*The BCL6* proto-oncogene suppresses p53 expression in germinal-centre B cells.** Nature 432:635-639, 2004 [link]
11/11/2004	Daphne	Efficient active transport of gene nanocarriers to the cell nucleus. PNAS 100:3878-3882, 2004 [link]
10/28/2004	Mike	MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell 119:75-86, 2004 [link]
10/14/2004	Mike	Inhibition of Akt kinase activity by a peptide spanning the betaA strand of the proto-oncogene TCL1. J Biol Chem 2004 Dec 17;279(51):53407-18 [link]
9/23/2004	Matt	Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 2004 Oct 8;306(5694):279-83 [link]
9/2/2004	Ksenia	Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature 2004 428:332-337 [link]
8/19/2004	Sam	Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain. Cell 117:773-786, 2004 [link]
8/5/2004	Hsaio-Wen	Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. Nat Cell Biol. 2004 May;6(5):386-8 [link]
7/22/2004	Rhine	Separate domains of AID are required for somatic hypermutation and class-switch recombination. Nat Immunol. 2004 Jul;5(7):707-12 [link]
7/8/2004	Francesca	Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer Research 64:3871-3877, 2004 [link]