Teitell Laboratory in the News

 

11.15.11: UCLA Scientists Uncover Mechanism that Regulates Human Pluripotent Stem Cell Metabolism and Cellular Differentiation Los Angeles/Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research – UCLA Researchers have discovered a novel mechanism in pluripotent stem cell metabolism that switches energy production from glycolysis to oxidative phosphorylation during stem cell differentiation.
--Association of American Cancer Institutes (AACI) [link]
--National Institute of Health (NIH) [link]
--California Institute for Regenerative Medicine (CIRM) [link]
--The EMBO Journal [link]
--UC Newsroom [link]
--UCLA Newsroom [link]
--Science Daily [link]
--Newswise [link]
--Science Codex [link]
--PhysOrg.com [link]
--ThirdAge.com [link]
--Examiner.com [link]
--HealthCanal.com [link]
--Medical News Today [link]

9.30.11: Nature Photonics Comments on Subcellular Sensing Collaborative Study from Zhang and Teitell Labs Nature Photonics – Researchers create an innovative method for mapping extracellular signalling at the molecular level. Using nanoimprint lithography and Jurkat T cells (a type of cell used in cancer research), they illustrated the pathway that cytokine molecules take when secreted during intercellular communication. [link]

7.29.11: Photothermal Nanoblade featured on podcast, "This Week in Microbiology" MicrobeWorld – Microbiology podcast hosts discuss the photothermal nanoblade as a new tool for the delivery of large cargo, enabling the dissection of intracellular pathogen lifecycles. [link]

6.9.11: Roche to provide UCLA Researchers with Access to Cutting Edge Technology Madison, WI – Roche and UCLA have reached an agreement that will provide the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA and UCLA's Jonsson Comprehensive Cancer Center with access to the latest in genomic technologies from Roche's research and development pipeline.
--Wall Street Journal[link]
--New York Times[link]
--Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research[link]
--UCLA Jonsson Comprehensive Cancer Center[link]
--BusinessWire[link]
--Newswise[link]
--Yahoo Finance[link]
--Genetic Engineering and Biotechnology News[link]
--Scimitar Equity Blog[link]
--Genome Web Daily News[link]
--Pressebox[link]
--Fresh News[link]
--Examiner[link]
--Fierce Biotech[link]
--The Street[link]
--EurekAlert[link]
--InvestorStemCell[link]

1.27.11: UCLA Researchers Develop New Tool for Efficient Large Cargo Delivery Into Mammalian Cells Chemical and Engineering News – Researchers have developed a photothermal nanoblade that cuts a resealable, micrometer-sized hole in the cell membrane, enabling efficient delivery of large cargos.

1.5.2011: California NanoSystems Institue (CNSI) 2010 Report highlights the Teitell lab Los Angeles/California NanoSystems Institute – Through a groundbreaking ABRAXIS/CNSI collaboration the Teitell lab is developing an interference based microscope to measure cell motion and growth. These measurements can be applied to live tumor cells undergoing drug treament to enable development of personalized drug therapies. (pg 11) Teitell publications on an important signaling pathway in B-cell development and a protein that imports RNA into the mitochondria are featured. (pg 13) [PDF]

10.21.2010: Teitell discusses DNA Methylation and Gene Regulation on Science Webinar: The Epigenetics Challenge Science AAAS – Epigenetics is being recognized as an increasingly important area of research that involves an understanding of the molecular mechanisms that influence the phenotypic outcome of the genome without alteration of the DNA sequence.

9.23.2010: Researchers Discover New Signaling Pathway that Controls Cell Development and Cancer Los Angeles/Johnson Comprehensive Cancer Center – Researchers at UCLA’s Jonsson Comprehensive Cancer Center have discovered a new cell signaling pathway that controls cell growth and development, a pathway that when defective helps promote the formation of several major forms of human cancer including lymphoma and leukemia.
--Association of American Cancer Institutes[link]
--UCLA Newsroom Video[link]
--MolecularStation[link]
--Health News Digest[link]
--DotMed[link]
--CIRM News Summary[link]
--Breast Cancer Network (BCN)[link]
--Science Magazine[link]

8.06.2010: Researchers Discover Protein that Shuttles RNA into Cell Mitochondria Los Angeles/Johnson Comprehensive Cancer Center – Researchers at UCLA’s Jonsson Comprehensive Cancer Center and the departments of Chemistry and Biochemistry and Pathology and Laboratory Medicine have uncovered a role for an essential cell protein in shuttling RNA into mitochondria, the energy-producing “power plant” of the cell.
-- UCLA Newsroom [link]
-- CIRM News Summary [link]
-- Health and Medicine News [link]
-- News Blaze [link]
-- EurekAlert [link]
-- ScienceDaily [link]
-- California NanoSystems Institute(CNSI) [link]
-- One India [link]
-- FARS News [link]
-- MusclesProduction [link]

7.22.2010: Valley Papers Explore Stem Cell Research for College Students The San Fernando Valley Sun and San Fernando Business Journal reported on a program that pairs Cal State University Northridge students with researchers from the UCLA Broad Stem Cell Research Center.
-- San Fernando Valley Sun [link]
-- San Fernadno Business Journal [link]

7.6.2010: Teitell comments on California Institute for Regenerative Medicine (CIRM) CSUN-UCLA BRIDGES Stem Cell Training Grant Program Northridge Magazine, CSUN, UCLA Pair Up to Prepare Stem Cell Researchers: Damaged hearts regenerate. Paralyzed children run again. The blind regain vision, and cancer is eradicated.

6.23.2010: Teitell provides Perspective on "Nuclear Role of WASp in the Pathogenesis of Dysregulated Th1-Immunity in Human Wiskott-Aldrich Syndrome in Science Translational Medicine Alternative Control: What's WASp Doing in the Nucleus? Wiskott-Aldrich syndrome (WAS) is a rare X-linked recessive immunodeficiency disorder of childhood that is caused by mutations in the WAS gene.....

10.10.2009: B-Cell Lymphoma Protected By SPAK Silencing ScienceDaily, Oct. 10, 2009 -- A group led by Dr. Michael Teitell at UCLA has demonstrated that misregulation of the protein SPAK may contribute to B-cell lymphoma development.

08.21.2009: Teitell lab receives $1.32M from CIRM Basic Biology Award San Francisco, Calif., August 20, 2009 –- A $16 million infusion from the California Institute for Regenerative Medicine, the state stem cell agency, will s

03.26.2009: Teitell comments on 'Noncoding DNA copy number variation links to gene expression in stem cells' in Nature Reports Stem Cells Mariano Loza Coll, March 2009 / Nature Reports Stem Cells -- A genome-wide study reveals an association between CNVs and gene activity in haematopoietic stem cells.

11.26.2008: Teitell comments on 'From One, many genetically different embryonic stem cells' in Nature Reports Stem Cells Monya Baker, November 2008 / Nature Reports Stem Cells -- Copy number variants crop up in routine ES cell culture.

08.04.2008: NLLS Honors Five Scientists for Outstanding Work in Blood Cancer Research Andrea Greif, White Plaines, NY, August 2008 / The Leukemia & Lymphoma Society -- The Leukemia & Lymphoma Society (LLS) has named five researchers as Stohlman Scholars, recognizing their outstanding contributions to the advancement of blood cancer research.  The honors will be officially announced at the LLS Stohlman Scholar Scientific Symposium, Nov. 6-7, in Kansas City, MO.
-- Reuters [link]
-- Apria [link]
-- PRNews Wire [link]
-- Globe Investor [link]
-- Therapeutics Daily [link]
-- Cancer Compass [link]

07.10.2008: Nature Reports Stem Cells; How to assess a stem cell genome Mike Teitell, July 2008 / Nature Reports Stem Cells -- As potential therapies derived from pluripotent stem-cell lines move towards the clinic, researchers have yet to address an essential, practical question: how should cells be screened for genetic variants that contribute to cancer or other diseases? The tools to address this question exist, but discussions on how to use them for this purpose are rare and uncoordinated.

06.27.2008: Teitell Lab Featured on JOVE (Journal of Visualized Experiments); Watch Online
-- Probing for Mitochondrial Complex Activity in Human Embryonic Stem Cells [watch]
In this video, we will show you how the mitochondrial respiratory chain complexes of human embryonic stem cells can be analyzed using in gel activity assays.
-- From MEFs to Matrigel 3: Passaging hESCs from Matrigel onto Matrigel [watch]
This video demonstrates how to maintain the growth of human embryonic stem cells (hESCs) in feeder cell-free conditions and how to continuously passage hESCs in feeder cell-free conditions. Confirmation of hESC pluripotency grown in feeder cell-free conditions by immunofluorescence microscopy is also demonstrated.
-- From MEFs to Matrigel 2: Splitting hESCs from MEFs onto Matrigel [watch]
This video demonstrates how to maintain the growth of human embryonic stem cells (hESCs) in feeder cell-free conditions and how to continuously passage hESCs in feeder cell-free conditions. Confirmation of hESC pluripotency grown in feeder cell-free conditions by immunofluorescence microscopy is also demonstrated.
-- From MEFs to Matrigel I: Passaging hESCs in the Presence of MEFs [watch]
This video demonstrates how to grow human embryonic stem cells (hESCs) on mouse embryonic fibroblast (MEF) feeder cells.

06.19.2008: Teitell comment on ChIP-seq ES cell pluripotency study in Nature Reports Stem Cells Monya Baker, June 2008 / Nature Reports Stem Cells -- An analysis of transcription factor binding sites finds clusters that clarify cooperative binding.

06.13.2008: Nature Photonics Research Highlights: FEOET from Chiou and Teitell lab Applied Physics Letters publication June 2008, Vol. 2, pg. 331/ Nature Photonics -- Scientists based in the USA and Austria report a new type of optoelectronic tweezers that uses floating electrodes. Their tweezers can drive the movement of water drops through an immersion of oil.

06.04.2008: Scientists Win $2.25 Million Grant to Fund Research into Prostate Cancer Stem Cells Los Angeles, CA, June 2008 / Jonsson Comprehensive Cancer Center -- A team of researchers from UCLA’s Jonsson Cancer Center and the Broad Stem Cell Research Center has received a $2.25 million grant to study prostate cancer stem cells and better define the role they play in cancer development, drug resistance and disease recurrence.

04.10.2008: Some human embryonic stem cells have more gene copies than others Lindsay Borthwick, April 2008 / Nature Reports Stem Cells -- In the past few years, with the development of new tools for examining the human genome, researchers have found large segments of DNA that are copied or deleted in different individuals so that some people have more than two copies, only one copy or no copies of certain genes.

03.27.2008: UCLA Researchers examine Human Embryonic Stem Cell Genome Los angeles, CA, March 2008 / EurekAlert! Public News List -- Stem cell researchers from UCLA used a high resolution technique to examine the genome, or total DNA content, of a pair of human embryonic stem cell lines and found that while both lines could form neurons, the lines had differences in the numbers of certain genes that could control such things as individual traits and disease susceptibility.
-- California NanoSystems Institute [link]
-- Innovations Report [link]
-- Medical News Today [link]
-- Huliq.com [link]
-- ScienceBlog.com [link]
-- Science Daily [link]
-- PhysOrg.com [link]
-- News Wise [link]
-- Genetic Engineering News [link]

02.01.2008: Most-accessed articles in Nanotechnology Philadelphia, PA, February 2008 / Nanotechnology -- A collaborative article from the Teitell and Gimzewski Labs, Single molecule transcription profiling with AFM (Reed, J., et. al., Nanotechnology, 2007 [link]), is one of the most-accessed articles in the interdisciplinary journal Nanotechnology for the year 2007.

08.02.2007: Recipients of the first round of SEED grants surveyed San Francisco, CA, August 2007 /Nature Reports Stem Cells/Baker -- A Nature Reports Stem Cell survey of researchers shows that though most grantees are using stem cell lines eligible for funding under federal law, they are using more lines that are not.

04.12.2007: Meet the Researcher from eNEWSLINE - Q & A with M. Teitell Los Angeles, CA, April 2007 /eNEWSLINE/Peter -- Dr. Teitell, can you tell us about your work? We’re using a powerful technique called restriction landmark genomic scanning to investigate the causes of NHL.

03.04.2007: Research by Dr. Mike Teitell identifying genes that when inactivated help cause B-cell non-Hodgkin's lymphoma (NHL) was featured in the March 4 issues of the trade publications Cancer Weekly, Oncology Business Week, Lab Business Week, Cancer Law Weekly, Genetics & Environmental Law Weekly, Law & Health Weekly, Biotech Law Weekly, Drug Week, Genomics & Genetics Weekly, Health Business Week, Biotech Week, Genetics & Environmental Health Week, Clinical Oncology Week, Proteomics Weekly, Hematology Week, Health & Medicine Week, Biotech Business Week, World Disease Weekly, Science Letter, Life Science Weekly and Drug Law Weekly. Teitell is an associate professor of pediatrics and pathology and laboratory medicine and a researcher at UCLA’s Jonsson Cancer Center.

02.23.2007: Scientists get funding to investigate how stem cells function Los Angeles, CA, Feb. 23 /UCLA Today Online/ -- The Proposition 71 bond measure that California voters approved more than two years ago to fund human embryonic stem cell research is finally making its first pay-off: UCLA scientists will receive more than $4 million over two years.

02.21.2007: UCLA receives stem cell grants Los Angeles, CA, Feb. 21 /Dailybruin/ -- UCLA researchers received grants totalling close to $4.2 million to investigate issues concerning human embryonic stem cells for the next two years.

02.21.2007: Research by Dr. Mike Teitell identifying genes that when inactivated help cause B-cell non-Hodgkin's lymphoma (NHL) was featured Jan. 30 in Yahoo! News, KTBS-TV (LA), Genetic Engineering News, PR News Wire, Medical News Today, EarthTimes.org, CancerFocus.net and PharmaLive.com. The story appeared Feb. 2 in GenomicsProteomics.com and in Bio-IT World.  Teitell is an associate professor of pediatrics and pathology and laboratory medicine and a researcher at UCLA’s Jonsson Cancer Center.

02.20.2007: California Awards First Stem Cell Research Grants; UCLA Scientists Garner 7 of 72 Grants Given UCLA News -- UCLA scientists have received seven of 72 seed grants awarded by the state to fund stem cell research, the first money distributed for work on human embryonic stem cells since California voters approved Proposition 71 in November 2004. Seed grant funding totaled $45 million.

02.16.2007: $45 Million Headed for Stem Cell Research in California Genetic Engineering & biotechnology News/Business Wire -- More than two years after voters approved a $3 billion program to fund stem cell research in California, the state has approved the first grants focused solely on human embryonic stem cell research.

01.20.2007: UCLA Researchers Discover Genes Linked to Lymphoma, Opening Way for New Targeted Drugs WHITE PLAINS, N.Y., Jan. 30 /PRNewswire/ -- Lymphoma is a blood cancer that affects more than 60,000 Americans each year. Researchers at The University of California Los Angeles have identified genes that when inactivated help cause B-cell non-Hodgkin's lymphoma (NHL).

Cancer Focus [link]
Genetic Engineering & biotechnology News [link]
Medical News Today [link]
Biocompare [link]
NewsRx [link]